Route A40 from direction Duisburg:

• If you come from the west from the A40 you can already leave the motorway at exit "Zentrum" or "Huttrop" and follow the signs to Zentrum/Universität.
  

Route A40 from direction Bochum:

• If you come from the east from the A40, take the exit "Essen-Frillendorf" then proceed along Frillendorfer Strasse till the second traffic lights appear. Turn right into Burggrafenstrasse, then at the second traffic lights turn left into Gerlingstrasse. After the second traffic lights you arrive at Schützenbahn 70 (block tower and the old building).

Route A52 from direction Düsseldorf:

• If you arrive from the A52 from Duesseldorf please take the exit "Essen-Sued" and follow the signs to the University of Essen (not Universitaetsklinikum). After passing the very high administrational building your destination is on the right side.